Human MMAB protein (Recombinant) (His-Tag) (STJP016817)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MMAB-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MMAB |
| Gene ID | 326625 |
| Uniprot ID | MMAB_HUMAN |
| Accession Number | AAH05054 |
| Immunogen | Human |
| Immunogen Region | 33-250aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in liver and skeletal muscle. |
| Function | Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA (Probable). |
| Protein Name | Corrinoid Adenosyltransferase MmabAtp -Co(Irrinoid Adenosyltransferase MmabMethylmalonic Aciduria Type B Protein |
| Database Links | Reactome: R-HSA-3359471Reactome: R-HSA-9759218 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Corrinoid Adenosyltransferase Mmab proteinAtp -Co(Irrinoid Adenosyltransferase Mmab proteinMethylmalonic Aciduria Type B Protein proteinMMAB protein |
Information sourced from Uniprot.org