Human MIS12 protein (Recombinant) (His-Tag) (STJP018035)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MIS12-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MIS12 |
| Gene ID | 79003 |
| Uniprot ID | MIS12_HUMAN |
| Accession Number | NP_076944 |
| Immunogen | Human |
| Immunogen Region | 1-205aa |
| Immunogen Sequence |
Additional Info
| Function | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. Essential for proper kinetochore microtubule attachments. |
| Protein Name | Protein Mis12 Homolog |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | ChromosomeCentromereKinetochoreAssociated With The Kinetochore |
| Alternative Protein Names | Protein Mis12 Homolog proteinMIS12 protein |
Information sourced from Uniprot.org