Human MIP-1 Beta (C-C Motif Chemokine 4) Antibody Pair (STJAP00249)
General Information
| Short Description | This MIP-1 Beta antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | CCL4 |
| Gene ID | 388372/6351 |
| Uniprot ID | CCL4_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human MIP-1 Beta protein.Detection Immunogen: Recombinant Human MIP-1 Beta protein. |
Additional Info
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
| Protein Name | C-C Motif Chemokine 4G-26 T-Lymphocyte-Secreted ProteinHc21Lymphocyte Activation Gene 1 ProteinLag-1Mip-1-Beta(1-69Macrophage Inflammatory Protein 1-BetaMip-1-BetaPat 744Protein H400Sis-GammaSmall-Inducible Cytokine A4T-Cell Activation Protein 2Act-2 Cleaved Into - Mip-1-Beta(3-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 4 antibody pairG-26 T-Lymphocyte-Secreted Protein antibody pairHc21 antibody pairLymphocyte Activation Gene 1 Protein antibody pairLag-1 antibody pairMip-1-Beta(1-69 antibody pairMacrophage Inflammatory Protein 1-Beta antibody pairMip-1-Beta antibody pairPat 744 antibody pairProtein H400 antibody pairSis-Gamma antibody pairSmall-Inducible Cytokine A4 antibody pairT-Cell Activation Protein 2 antibody pairAct-2 Cleaved Into - Mip-1-Beta(3-69 antibody pairCCL4 antibody pairLAG1 antibody pairMIP1B antibody pairSCYA4 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human MIP-1 Beta (C-C Motif Chemokine 4) Antibody Pair (STJAP00249)
This antibody pair detects human MIP-1 Beta, also known as C-C Motif Chemokine 4 (UniProt P13236). Reactivity is confirmed for human samples only.
The capture antibody is supplied unconjugated and the detection antibody is biotin-conjugated. Both are polyclonal antibodies raised in goat, supplied at 0.5 mg/mL, and formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This antibody pair has been validated for use in ELISA. No other assay formats are specified for this product.
Both the capture and detection antibodies were raised against recombinant human MIP-1 Beta protein. Both antibodies have been purified by antigen affinity chromatography.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain antibody integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.