Human MIP-1 alpha (MIP-1 alpha) Antibody Pair (STJAP00734)
General Information
| Short Description | This MIP-1 alpha antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R05-5W2/R04-9Z4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CCL3 |
| Gene ID | 6348 |
| Uniprot ID | CCL3_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Post Translational Modifications | N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3G0/G1 Switch Regulatory Protein 19-1Macrophage Inflammatory Protein 1-AlphaMip-1-AlphaPat 464.1Sis-BetaSmall-Inducible Cytokine A3Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69Ld78-Alpha(4-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 3 antibody pairG0/G1 Switch Regulatory Protein 19-1 antibody pairMacrophage Inflammatory Protein 1-Alpha antibody pairMip-1-Alpha antibody pairPat 464.1 antibody pairSis-Beta antibody pairSmall-Inducible Cytokine A3 antibody pairTonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69 antibody pairLd78-Alpha(4-69 antibody pairCCL3 antibody pairG0S19-1 antibody pairMIP1A antibody pairSCYA3 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human MIP-1 alpha (MIP-1 alpha) Antibody Pair (STJAP00734)
This antibody pair is designed to detect human MIP-1 alpha (CCL3, UniProt P10147) and has confirmed reactivity with human samples only.
This antibody pair is validated for use in ELISA. No other assay formats are listed for this product.
Both antibodies are supplied as unconjugated, affinity-purified rabbit monoclonal IgGs at 1 mg/mL, formulated in 0.01M PBS at pH 7.2. The clone IDs are R05-5W2 and R04-9Z4.
Working dilutions for both the capture and detection antibodies are to be determined by the end user. Titration experiments are recommended to establish optimal concentrations for each specific experimental setup.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C, and avoid repeated freeze/thaw cycles to maintain activity.
Both monoclonal antibodies were raised in rabbit against a recombinant human MIP-1 alpha protein. No specific immunogen region is listed for this product.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.