Human Mimitin/NDUFAF2 protein (Recombinant) (His-Tag) (STJP017268)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Mimitin/NDUFAF2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% Glycerol, 200mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDUFAF2 |
| Gene ID | 91942 |
| Uniprot ID | NDUF2_HUMAN |
| Accession Number | NP_777549 |
| Immunogen | Human |
| Immunogen Region | 1-169aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highly expressed in ESCC cells. Also expressed in heart, skeletal muscle, liver, and in fibroblasts. |
| Function | Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Is involved in the initial steps of cilia formation, including removal of CP110 from the mother centrioles, docking of membrane vesicles to the mother centrioles, and establishment of the transition zone. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Assembly Factor 2B17.2-LikeB17.2lMimitinMyc-Induced Mitochondrial ProteinMmtnNdufa12-Like Protein |
| Database Links | Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Assembly Factor 2 proteinB17.2-Like proteinB17.2l proteinMimitin proteinMyc-Induced Mitochondrial Protein proteinMmtn proteinNdufa12-Like Protein proteinNDUFAF2 proteinNDUFA12L protein |
Information sourced from Uniprot.org