Human MGA protein (Recombinant) (N-His) (STJP005673)

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STJP005673
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Short Description :Recombinant-Human MGA-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:MGA
Gene ID:23269
Uniprot ID:MGAP_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Leu2450-Val2733
Function Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor.
Protein Name Max Gene-Associated Protein
Max Dimerization Protein 5
Database Links Reactome: R-HSA-8953750
Cellular Localisation Nucleus
Alternative Protein Names Max Gene-Associated Protein protein
Max Dimerization Protein 5 protein
MGA protein
KIAA0518 protein
MAD5 protein

Information sourced from Uniprot.org

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