Human MGA (Maltase Glucoamylase, Intestinal) Sandwich ELISA Kit (STJE0010572)

SPECIFICATIONS
STJE0010572
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General Information

Short DescriptionThis MGA Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
ApplicationsELISA
ReactivityHuman
Sensitivity0.63ng/mL
Detection Limit1.56-100ng/mL
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Storage InstructionStore the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time4.5 hrs

Target Information

Gene SymbolMGA
Gene ID23269
Uniprot IDMGAP_HUMAN
Sample Typetissue homogenates, cell lysates or other biological fluids.

Additional Info

Tissue Specificity Highly expressed in germ cells and granulosa cells.
Post Translational Modifications
Function Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor.
Protein Name Max Gene-Associated Protein
Max Dimerization Protein 5
Database Links Reactome: R-HSA-8953750
Cellular Localisation Nucleus
Alternative ELISA Names Max Gene-Associated Protein ELISA kit
Max Dimerization Protein 5 ELISA kit
MGA ELISA kit
KIAA0518 ELISA kit
MAD5 ELISA kit
output

Information sourced from Uniprot.org

Citations

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