Human MESDC2 protein (Recombinant) (His-Tag) (STJP017070)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MESDC2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MESD |
| Gene ID | 23184 |
| Uniprot ID | MESD_HUMAN |
| Accession Number | NP_055969 |
| Immunogen | Human |
| Immunogen Region | 34-234aa |
| Immunogen Sequence |
Additional Info
| Function | Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells. |
| Protein Name | Lrp Chaperone MesdLdlr Chaperone MesdMesoderm Development Lrp Chaperone MesdMesoderm Development Candidate 2Mesoderm Development ProteinRenal Carcinoma Antigen Ny-Ren-61 |
| Database Links | |
| Cellular Localisation | Endoplasmic ReticulumReleased From Apoptotic Cells And Shed Photoreceptor Outer Segments |
| Alternative Protein Names | Lrp Chaperone Mesd proteinLdlr Chaperone Mesd proteinMesoderm Development Lrp Chaperone Mesd proteinMesoderm Development Candidate 2 proteinMesoderm Development Protein proteinRenal Carcinoma Antigen Ny-Ren-61 proteinMESD proteinKIAA0081 proteinMESDC2 proteinMESDM proteinUNQ1911 proteinPRO4369 protein |
Information sourced from Uniprot.org