Human MEMO1 protein (Recombinant) (His-Tag) (STJP017728)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MEMO1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 50% Glycerol, 5mM DTT, 300mM NaCl, 2mM EDTA |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MEMO1 |
| Gene ID | 51072 |
| Uniprot ID | MEMO1_HUMAN |
| Accession Number | NP_057039 |
| Immunogen | Human |
| Immunogen Region | 1-297aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMMSNRV VCREASHAGS WYTASGPQLN AQLEGWLSQV QSTKRPARAI IAPHAGYTYC GSCAAHAYKQ VDPSITRRIF ILGPSHHVPL SRCALSSVDI YRTPLYDLRI DQKIYGELWK TGMFERMSLQ TDEDEHSIEM HLPYTAKAME SHKDEFTIIP VLVGALSESK EQEFGKLFSK YLADPSNLFV VSSDFCHWGQ RFRYSYYD |
Additional Info
| Function | May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. |
| Protein Name | Protein Memo1C21orf19-Like ProteinHepatitis C Virus Ns5a-Transactivated Protein 7Hcv Ns5a-Transactivated Protein 7Mediator Of Erbb2-Driven Cell Motility 1Mediator Of Cell Motility 1Memo-1 |
| Database Links | Reactome: R-HSA-6785631 |
| Cellular Localisation | |
| Alternative Protein Names | Protein Memo1 proteinC21orf19-Like Protein proteinHepatitis C Virus Ns5a-Transactivated Protein 7 proteinHcv Ns5a-Transactivated Protein 7 proteinMediator Of Erbb2-Driven Cell Motility 1 proteinMediator Of Cell Motility 1 proteinMemo-1 proteinMEMO1 proteinC2orf4 proteinMEMO proteinNS5ATP7 proteinCGI-27 protein |
Information sourced from Uniprot.org