Human MD-1 protein (Recombinant) (His-Tag) (STJP018322)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018322
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General Information

Short DescriptionRecombinant-Human MD-1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing, 10% Glycerol, 0.4M urea
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolLY86
Gene ID9450
Uniprot IDLY86_HUMAN
Accession NumberNP_004262
ImmunogenHuman
Immunogen Region21-162aa
Immunogen SequenceGGGGKAW PTHVVCSDSG LEVLYQSCDP LQDFGFSVEK CSKQLKSNIN IRFGIILRED IKELFLDLAL MSQGSSVLNF SYPICEAALP KFSFCGRRKG EQIYYAGPVN NPEFTIPQGE YQVLLELYTE KRSTVACANA TIMCS

Additional Info

Tissue Specificity Highly expressed in B-cells, monocytes and tonsil.
Function May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.
Protein Name Lymphocyte Antigen 86
Ly-86
Protein Md-1
Database Links Reactome: R-HSA-166016
Cellular Localisation Secreted
Extracellular Space
Associated With Cd180 At The Cell Surface
Alternative Protein Names Lymphocyte Antigen 86 protein
Ly-86 protein
Protein Md-1 protein
LY86 protein
MD1 protein

Information sourced from Uniprot.org

Citations

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