Human MCSF (Macrophage Colony-Stimulating Factor 1) Antibody Pair (STJAP00247)
SPECIFICATIONS
ClonalityMonoclonal/Monoclonal
HostRabbit/Rabbit
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Human MCSF protein.Detection Immunogen: Recombinant Human MCSF protein.
General Information
| Short Description | This MCSF antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A.Detection Purification: Protein A. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | CSF1 |
| Gene ID | 1435 |
| Uniprot ID | CSF1_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human MCSF protein.Detection Immunogen: Recombinant Human MCSF protein. |
Additional Info
| Function | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. |
| Protein Name | Macrophage Colony-Stimulating Factor 1Csf-1M-CsfMcsfLanimostimProteoglycan Macrophage Colony-Stimulating FactorPg-M-Csf Cleaved Into - Processed Macrophage Colony-Stimulating Factor 1 - Macrophage Colony-Stimulating Factor 1 43 Kda Subunit |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-449836Reactome: R-HSA-6783783Reactome: R-HSA-8957275Reactome: R-HSA-9680350Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinProcessed Macrophage Colony-Stimulating Factor 1: SecretedExtracellular Space |
| Alternative Antibody Pair Names | Macrophage Colony-Stimulating Factor 1 antibody pairCsf-1 antibody pairM-Csf antibody pairMcsf antibody pairLanimostim antibody pairProteoglycan Macrophage Colony-Stimulating Factor antibody pairPg-M-Csf Cleaved Into - Processed Macrophage Colony-Stimulating Factor 1 - Macrophage Colony-Stimulating Factor 1 43 Kda Subunit antibody pairCSF1 antibody pair |
Information sourced from Uniprot.org