Human MCP-4 (MCP-4) Antibody Pair (STJAP00982)
General Information
| Short Description | This MCP-4 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL/0.5-4ug/mL |
| Dilution Range | 1:1000-1:10000 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Detection | Colorimetric method;ELISA;Sandwich |
Target Information
| Gene Symbol | CCL13 |
| Gene ID | 6357 |
| Uniprot ID | CCL13_HUMAN |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain. |
| Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. |
| Protein Name | C-C Motif Chemokine 13Ck-Beta-10Monocyte Chemoattractant Protein 4Monocyte Chemotactic Protein 4Mcp-4Ncc-1Small-Inducible Cytokine A13 Cleaved Into - C-C Motif Chemokine 13 - Long Chain - C-C Motif Chemokine 13 - Medium Chain - C-C Motif Chemokine 13 - Short Chain |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 13 antibody pairCk-Beta-10 antibody pairMonocyte Chemoattractant Protein 4 antibody pairMonocyte Chemotactic Protein 4 antibody pairMcp-4 antibody pairNcc-1 antibody pairSmall-Inducible Cytokine A13 Cleaved Into - C-C Motif Chemokine 13 - Long Chain - C-C Motif Chemokine 13 - Medium Chain - C-C Motif Chemokine 13 - Short Chain antibody pairCCL13 antibody pairMCP4 antibody pairNCC1 antibody pairSCYA13 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human MCP-4 (MCP-4) Antibody Pair (STJAP00982)
This antibody pair detects human MCP-4 (UniProt Q99616) and has confirmed reactivity against human samples only. It is intended for research use only and is not validated for non-human species.
The pair consists of two rabbit-raised antibodies: the capture antibody is unconjugated and supplied at 0.5 mg/mL, while the detection antibody is biotinylated and supplied at a concentration range of 0.5 to 4 ug/mL.
This antibody pair has been validated for use in sandwich ELISA with colorimetric detection. No other assay formats are listed for this product.
This antibody pair has been tested with serum, plasma, and other biological fluids. Researchers should validate performance in any sample type not explicitly listed before use in formal experiments.
The recommended dilution range is 1:1000 to 1:10000. Optimal dilutions may vary depending on specific experimental conditions and should be determined empirically by the end user.
Both components should be stored at -20 degrees Celsius for long-term storage. Repeated freeze-thaw cycles should be avoided to maintain product integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.