Human MC1R protein (Recombinant) (N-His) (STJP014596)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MC1R-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 2% Mannitol |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for this information. |
Target Information
| Gene Symbol | MC1R |
| Gene ID | 4157 |
| Uniprot ID | MSHR_HUMAN |
| Immunogen | Human |
| Immunogen Region | [Met1-Glu37] & [Glu94-Asn118] & [Asp141-Arg163] & [Ala212-Ala240] |
Additional Info
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes. |
| Protein Name | Melanocyte-Stimulating Hormone ReceptorMsh-RMelanocortin Receptor 1Mc1-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Melanocyte-Stimulating Hormone Receptor proteinMsh-R proteinMelanocortin Receptor 1 proteinMc1-R proteinMC1R proteinMSHR protein |
Information sourced from Uniprot.org