Human MBIP protein (Recombinant) (N-His) (STJP014735)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MBIP-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM Tris-HCl, pH 8.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | MBIP |
| Gene ID | 51562 |
| Uniprot ID | MBIP1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro344 |
Additional Info
| Function | Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
| Protein Name | Map3k12-Binding Inhibitory Protein 1Mapk Upstream Kinase-Binding Inhibitory ProteinMuk-Binding Inhibitory Protein |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusCytoplasmShows A Cytoplasmic Localization When Coexpressed With Map3k12 |
| Alternative Protein Names | Map3k12-Binding Inhibitory Protein 1 proteinMapk Upstream Kinase-Binding Inhibitory Protein proteinMuk-Binding Inhibitory Protein proteinMBIP proteinBM-015 protein |
Information sourced from Uniprot.org