Human MBIP protein (Recombinant) (His-Tag) (STJP018564)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human MBIP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing, 10% Glycerol, 0.4M urea |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MBIP |
| Gene ID | 51562 |
| Uniprot ID | MBIP1_HUMAN |
| Accession Number | NP_057670 |
| Immunogen | Human |
| Immunogen Region | 1-344aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAAATEL NRPSSGDRNL ERRCRPNLSR EVLYEIFRSL HTLVGQLDLR DDVVKITIDW NKLQSLSAFQ PALLFSALEQ HILYLQPFLA KLQSPIKEEN TTAVEEIGRT EMGNKNEVND KFSIGDLQEE EKHKESDLRD VKKTQIHFDP EVVQIKAGKA EIDRRISAFI ERKQAEINEN NVREFCNVID CNQENSCART DAIFTPYP |
Additional Info
| Tissue Specificity | Ubiquitous. High expression seen in the heart and lung. |
| Function | Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
| Protein Name | Map3k12-Binding Inhibitory Protein 1Mapk Upstream Kinase-Binding Inhibitory ProteinMuk-Binding Inhibitory Protein |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusCytoplasmShows A Cytoplasmic Localization When Coexpressed With Map3k12 |
| Alternative Protein Names | Map3k12-Binding Inhibitory Protein 1 proteinMapk Upstream Kinase-Binding Inhibitory Protein proteinMuk-Binding Inhibitory Protein proteinMBIP proteinBM-015 protein |
Information sourced from Uniprot.org