Human MAX protein (Recombinant) (N-GST) (STJP005017)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MAX-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | MAX |
| Gene ID | 4149 |
| Uniprot ID | MAX_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser2-Ser160 |
Additional Info
| Post Translational Modifications | Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes. |
| Function | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements. |
| Protein Name | Protein MaxClass D Basic Helix-Loop-Helix Protein 4Bhlhd4Myc-Associated Factor X |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-69202Reactome: R-HSA-69656Reactome: R-HSA-8953750 |
| Cellular Localisation | NucleusCell ProjectionDendrite |
| Alternative Protein Names | Protein Max proteinClass D Basic Helix-Loop-Helix Protein 4 proteinBhlhd4 proteinMyc-Associated Factor X proteinMAX proteinBHLHD4 protein |
Information sourced from Uniprot.org