Human MAT1A protein (Recombinant) (N-His) (STJP009636)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP009636
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General Information

Short DescriptionRecombinant-Human MAT1A-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolMAT1A
Gene ID4143
Uniprot IDMETK1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionGly16-Phe395

Additional Info

Post Translational Modifications S-nitrosylation of Cys-120 inactivates the enzyme. An intrachain disulfide bond can be formed. The protein structure shows that the relevant Cys residues are in a position that would permit formation of a disulfide bond.
Function Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
Protein Name S-Adenosylmethionine Synthase Isoform Type-1
Adomet Synthase 1
Methionine Adenosyltransferase 1
Mat 1
Methionine Adenosyltransferase I/Iii
Mat-I/Iii
Database Links Reactome: R-HSA-156581
Reactome: R-HSA-1614635
Reactome: R-HSA-2408508
Reactome: R-HSA-5579024
Cellular Localisation
Alternative Protein Names S-Adenosylmethionine Synthase Isoform Type-1 protein
Adomet Synthase 1 protein
Methionine Adenosyltransferase 1 protein
Mat 1 protein
Methionine Adenosyltransferase I/Iii protein
Mat-I/Iii protein
MAT1A protein
AMS1 protein
MATA1 protein

Information sourced from Uniprot.org

Citations

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