Name: Human MAT1A protein (Recombinant) (His-Tag) (STJP016630)
SKU: STJP016630
Availability: InStock

Human MAT1A protein (Recombinant) (His-Tag) (STJP016630)

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STJP016630

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Short Description :	Recombinant-Human MAT1A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	0.5 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1M NaCl, 10% Glycerol
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol:	MAT1A
Gene ID:	4143
Uniprot ID:	METK1_HUMAN
Accession Number:	NP_000420.1
Immunogen:	Human
Immunogen Region:	1-395aa
Immunogen Sequence:	MNGPVDGLCD HSLSEGVFMF TSESVGEGHP DKICDQISDA VLDAHLKQDP NAKVACETVC KTGMVLLCGE ITSMAMVDYQ RVVRDTIKHI GYDDSAKGFD FKTCNVLVAL EQQSPDIAQC VHLDRNEEDV GAGDQGLMFG YATDETEECM PLTIILAHKL NARMADLRRS GLLPWLRPDS KTQVTVQYMQ DNGAVIPVRI HTIVIS

Tissue Specificity	Expressed in liver.
Post Translational Modifications	S-nitrosylation of Cys-120 inactivates the enzyme. An intrachain disulfide bond can be formed. The protein structure shows that the relevant Cys residues are in a position that would permit formation of a disulfide bond.
Function	Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
Protein Name	S-Adenosylmethionine Synthase Isoform Type-1 Adomet Synthase 1 Methionine Adenosyltransferase 1 Mat 1 Methionine Adenosyltransferase I/Iii Mat-I/Iii
Database Links	Reactome: R-HSA-156581 Reactome: R-HSA-1614635 Reactome: R-HSA-2408508 Reactome: R-HSA-5579024
Cellular Localisation
Alternative Protein Names	S-Adenosylmethionine Synthase Isoform Type-1 protein Adomet Synthase 1 protein Methionine Adenosyltransferase 1 protein Mat 1 protein Methionine Adenosyltransferase I/Iii protein Mat-I/Iii protein MAT1A protein AMS1 protein MATA1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP009636	Human MAT1A protein (Recombinant) (N-His) (STJP009636)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP019170	Human FGB protein (Recombinant) (His-Tag) (STJP019170)	E.coli	SDS-PAGE
STJP019149	Human PYCR2 protein (Recombinant) (His-Tag) (STJP019149)	E.coli	SDS-PAGE
STJP019163	Human ALDH6A1 protein (Recombinant) (His-Tag) (STJP019163)	E.coli	SDS-PAGE
STJP019189	Human UBE2Q2 protein (Recombinant) (His-Tag) (STJP019189)	E.coli	SDS-PAGE

Human MAT1A protein (Recombinant) (His-Tag) (STJP016630)

General Information