Human MAT1a (Methionine Adenosyltransferase I Alpha) Sandwich ELISA Kit (STJE0010498)
SPECIFICATIONS
General Information
| Short Description | This MAT1a Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.255ng/mL |
| Detection Limit | 0.625-40ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | MAT1A |
| Gene ID | 4143 |
| Uniprot ID | METK1_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in liver. |
| Post Translational Modifications | S-nitrosylation of Cys-120 inactivates the enzyme. An intrachain disulfide bond can be formed. The protein structure shows that the relevant Cys residues are in a position that would permit formation of a disulfide bond. |
| Function | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. |
| Protein Name | S-Adenosylmethionine Synthase Isoform Type-1Adomet Synthase 1Methionine Adenosyltransferase 1Mat 1Methionine Adenosyltransferase I/IiiMat-I/Iii |
| Database Links | Reactome: R-HSA-156581Reactome: R-HSA-1614635Reactome: R-HSA-2408508Reactome: R-HSA-5579024 |
| Cellular Localisation | |
| Alternative ELISA Names | S-Adenosylmethionine Synthase Isoform Type-1 ELISA kitAdomet Synthase 1 ELISA kitMethionine Adenosyltransferase 1 ELISA kitMat 1 ELISA kitMethionine Adenosyltransferase I/Iii ELISA kitMat-I/Iii ELISA kitMAT1A ELISA kitAMS1 ELISA kitMATA1 ELISA kit |
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Information sourced from Uniprot.org