Human MAP3K1 protein (Recombinant) (N-His) (STJP005306)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MAP3K1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | MAP3K1 |
| Gene ID | 4214 |
| Uniprot ID | M3K1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ile1307-Arg1509 |
Additional Info
| Function | Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. May phosphorylate the MAPK8/JNK1 kinase. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. |
| Protein Name | Mitogen-Activated Protein Kinase Kinase Kinase 1Mapk/Erk Kinase Kinase 1Mek Kinase 1Mekk 1 |
| Database Links | Reactome: R-HSA-166058Reactome: R-HSA-2871796Reactome: R-HSA-933542Reactome: R-HSA-975138Reactome: R-HSA-975871 |
| Cellular Localisation | |
| Alternative Protein Names | Mitogen-Activated Protein Kinase Kinase Kinase 1 proteinMapk/Erk Kinase Kinase 1 proteinMek Kinase 1 proteinMekk 1 proteinMAP3K1 proteinMAPKKK1 proteinMEKK proteinMEKK1 protein |
Information sourced from Uniprot.org