| Short Description : | Recombinant-Human MAO-A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MAOA |
| Gene ID: | 4128 |
| Uniprot ID: | AOFA_HUMAN |
| Accession Number: | NP_000231 |
| Immunogen: | Human |
| Immunogen Region: | 1-497aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMENQEKA SIAGHMFDVV VIGGGISGLS AAKLLTEYGV SVLVLEARDR VGGRTYTIRN EHVDYVDVGG AYVGPTQNRI LRLSKELGIE TYKVNVSERL VQYVKGKTYP FRGAFPPVWN PIAYLDYNNL WRTIDNMGKE IPTDAPWEAQ HADKWDKMTM KELIDKICWT KTARRFAYLF VNINVTSEPH EVSALWFLWY VKQCGGTT |
| Tissue Specificity | Heart, liver, duodenum, blood vessels and kidney. |
| Function | Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Preferentially oxidizes serotonin. Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline. |
| Protein Name | Amine Oxidase Flavin-Containing AMonoamine Oxidase Type AMao-A |
| Database Links | Reactome: R-HSA-141333Reactome: R-HSA-181430Reactome: R-HSA-379397Reactome: R-HSA-379398Reactome: R-HSA-379401Reactome: R-HSA-380612Reactome: R-HSA-5579012Reactome: R-HSA-6785807 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmic Side |
| Alternative Protein Names | Amine Oxidase Flavin-Containing A proteinMonoamine Oxidase Type A proteinMao-A proteinMAOA protein |
Information sourced from Uniprot.org
