Human MAN1B1 protein (Recombinant) (C-His) (STJP013760)

Name: Human MAN1B1 protein (Recombinant) (C-His) (STJP013760)
SKU: STJP013760-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP013760-100

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Short Description	Recombinant-Human MAN1B1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Formulation	Supplied as a 0.22 Mu m filtered solution in 20mM PB, 50mM NaCl, 5% Sucrose, 5% Mannitol, 0.05% Tween 80, pH 8.0.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Function	Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2).
Protein Name	Endoplasmic Reticulum Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase Er Alpha-1 -2-Mannosidase Er Mannosidase 1 Erman1 Man9glcnac2-Specific-Processing Alpha-Mannosidase Mannosidase Alpha Class 1b Member 1
Database Links	Reactome: R-HSA-4793950 Reactome: R-HSA-901032 Reactome: R-HSA-9694548
Cellular Localisation	Endoplasmic Reticulum Membrane Single-Pass Type Ii Membrane Protein
Alternative Protein Names	Endoplasmic Reticulum Mannosyl-Oligosaccharide 1 -2-Alpha-Mannosidase protein Er Alpha-1 -2-Mannosidase protein Er Mannosidase 1 protein Erman1 protein Man9glcnac2-Specific-Processing Alpha-Mannosidase protein Mannosidase Alpha Class 1b Member 1 protein MAN1B1 protein UNQ747 protein PRO1477 protein

Information sourced from Uniprot.org