Name: Human Macrophage migration inhibitory factor/MIF protein (Recombinant) (No tag) (STJP003061)
SKU: STJP003061
Availability: InStock

Human Macrophage migration inhibitory factor/MIF protein (Recombinant) (No tag) (STJP003061)

SKU:

STJP003061

£148.50 - £493.50

Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of 20mM PB, 150mM NaCl, pH 7.4/20mM PB, 150mM NaCl, pH 7.4, 50% Glycerol
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 1 EU/Mu g of the protein by LAL method.

Gene Symbol:	MIF
Gene ID:	4282
Uniprot ID:	MIF_HUMAN
Immunogen Region:	Met1-Ala115
Immunogen:	Recombinant human Macrophage migration inhibitory factor/MIF Protein is produced by E.coli expression system. The target protein is expressed with sequence (Met1-Ala115) of human Macrophage migration inhibitory factor/MIF (Accession #NP_002406.1) fus
Immunogen Sequence:	PGPPAGSPRVSSDPRADLDS AVLLTRSLLADTRQLAAQMR DKFPADGDHSLDSLPTLAMS AGTLGSLQLPGVLTRLRVDL MSYLRHVQWLRRAGGPSLKT LEPELGALQARLERLLRRLQ LLMSRLALPQAAPDQPVIPL GPPASAWGSIRAAHAILGGL HLTLDWAVRGLLLLKTRL

Function	Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Protein Name	Macrophage Migration Inhibitory Factor Mif Glycosylation-Inhibiting Factor Gif L-Dopachrome Isomerase L-Dopachrome Tautomerase Phenylpyruvate Tautomerase
Database Links	Reactome: R-HSA-202733 Reactome: R-HSA-6798695 Reactome: R-HSA-8950505
Cellular Localisation	Secreted Cytoplasm Does Not Have A Cleavable Signal Sequence And Is Secreted Via A Specialized Non-Classical Pathway Secreted By Macrophages Upon Stimulation By Bacterial Lipopolysaccharide (Lps) Or By M Tuberculosis Antigens
Alternative Protein Names	Macrophage Migration Inhibitory Factor protein Mif protein Glycosylation-Inhibiting Factor protein Gif protein L-Dopachrome Isomerase protein L-Dopachrome Tautomerase protein Phenylpyruvate Tautomerase protein MIF protein GLIF protein MMIF protein

Information sourced from Uniprot.org

Model	Name	Host	Reactivity	Application
STJP002982	Mouse Macrophage migration inhibitory factor/MIF protein (Recombinant) (N-hFC) (STJP002982)	HEK293 cells
STJAP00460	Human MIF (Macrophage Migration Inhibitory Factor) Antibody Pair (STJAP00460)	Mouse/Mouse	Human	ELISA
STJE0019758	Human MIF (Macrophage Migration Inhibitory Factor) Sandwich ELISA Kit (STJE0019758)		Human	ELISA
STJE0005893	Rat Mif (Macrophage migration inhibitory factor) Sandwich ELISA Kit (STJE0005893)		Rat	ELISA
STJE0004768	Mouse Mif (Macrophage migration inhibitory factor) Sandwich ELISA Kit (STJE0004768)		Mouse	ELISA

Human Macrophage migration inhibitory factor/MIF protein (Recombinant) (No tag) (STJP003061)