Human LZTS2 protein (Recombinant) (N-His) (STJP010994)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LZTS2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | LZTS2 |
| Gene ID | 84445 |
| Uniprot ID | LZTS2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser320-Glu539 |
Additional Info
| Function | Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. |
| Protein Name | Leucine Zipper Putative Tumor Suppressor 2Hlzts2Protein Lapser1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeLocalized To The Centrosome Throughout The Cell CycleLocalized To The Midbody In Cells Undergoing Cytokinesis |
| Alternative Protein Names | Leucine Zipper Putative Tumor Suppressor 2 proteinHlzts2 proteinProtein Lapser1 proteinLZTS2 proteinKIAA1813 proteinLAPSER1 protein |
Information sourced from Uniprot.org