Human LYPLA2 protein (Recombinant) (N-His) (STJP003423)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP003423
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General Information

Short DescriptionRecombinant-Human LYPLA2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolLYPLA2
Gene ID11313
Uniprot IDLYPA2_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionMet1-Thr196

Additional Info

Function Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.
Protein Name Acyl-Protein Thioesterase 2
Apt-2
Lysophospholipase Ii
Lpl-Ii
Lysopla Ii
Palmitoyl-Protein Hydrolase
Database Links Reactome: R-HSA-373760
Cellular Localisation Cytoplasm
Alternative Protein Names Acyl-Protein Thioesterase 2 protein
Apt-2 protein
Lysophospholipase Ii protein
Lpl-Ii protein
Lysopla Ii protein
Palmitoyl-Protein Hydrolase protein
LYPLA2 protein
APT2 protein

Information sourced from Uniprot.org

Citations

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