Human LYPLA2 protein (Recombinant) (C-His) (STJP014307)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LYPLA2-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 1mM DTT, 100mM NaCl, pH 8.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | LYPLA2 |
| Gene ID | 11313 |
| Uniprot ID | LYPA2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Val231 |
Additional Info
| Function | Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide. |
| Protein Name | Acyl-Protein Thioesterase 2Apt-2Lysophospholipase IiLpl-IiLysopla IiPalmitoyl-Protein Hydrolase |
| Database Links | Reactome: R-HSA-373760 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Acyl-Protein Thioesterase 2 proteinApt-2 proteinLysophospholipase Ii proteinLpl-Ii proteinLysopla Ii proteinPalmitoyl-Protein Hydrolase proteinLYPLA2 proteinAPT2 protein |
Information sourced from Uniprot.org