Human LSR (Lipolysis Stimulated Lipoprotein Receptor) Sandwich ELISA Kit Ready-To-Use Kit (STJE0016818)
SPECIFICATIONS
General Information
| Short Description | This LSR Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.056ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | LSR |
| Gene ID | 51599 |
| Uniprot ID | LSR_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation at Ser-365 by MAPK8/JNK1 and MAPK9/JNK2 may be required for exclusive localization at tricellular tight junstions. Polyubiquitinated at Lys-638 via 'Lys-63'-linked ubiquitin chains.deubiquitinated by USP53. |
| Function | Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells. Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions. |
| Protein Name | Lipolysis-Stimulated Lipoprotein ReceptorAngulin-1 |
| Database Links | Reactome: R-HSA-8964038Reactome: R-HSA-8964046 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionLocated At Tricellular Contacts |
| Alternative ELISA Names | Lipolysis-Stimulated Lipoprotein Receptor ELISA kitAngulin-1 ELISA kitLSR ELISA kitILDR3 ELISA kitLISCH ELISA kit |
| output |
Information sourced from Uniprot.org