Human LSR (Lipolysis Stimulated Lipoprotein Receptor) Sandwich ELISA Kit (STJE0010431)

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STJE0010431
£421.50 - £586.50
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Short Description :This LSR Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:0.056ng/mL
Detection Limit:0.156-10ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:LSR
Gene ID:51599
Uniprot ID:LSR_HUMAN
Sample Type:tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylation at Ser-365 by MAPK8/JNK1 and MAPK9/JNK2 may be required for exclusive localization at tricellular tight junstions. Polyubiquitinated at Lys-638 via 'Lys-63'-linked ubiquitin chains.deubiquitinated by USP53.
Function Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells. Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions.
Protein Name Lipolysis-Stimulated Lipoprotein Receptor
Angulin-1
Database Links Reactome: R-HSA-8964038
Reactome: R-HSA-8964046
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Tight Junction
Located At Tricellular Contacts
Alternative ELISA Names Lipolysis-Stimulated Lipoprotein Receptor ELISA kit
Angulin-1 ELISA kit
LSR ELISA kit
ILDR3 ELISA kit
LISCH ELISA kit
output

Information sourced from Uniprot.org