Human LRRC59 protein (Recombinant) (His-Tag) (STJP018452)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human LRRC59-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT, 2mM EDTA |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LRRC59 |
| Gene ID | 55379 |
| Uniprot ID | LRC59_HUMAN |
| Accession Number | NP_060979 |
| Immunogen | Human |
| Immunogen Region | 1-244aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMTKAGSK GGNLRDKLDG NELDLSLSDL NEVPVKELAA LPKATILDLS CNKLTTLPSD FCGLTHLVKL DLSKNKLQQL PADFGRLVNL QHLDLLNNKL VTLPVSFAQL KNLKWLDLKD NPLDPVLAKV AGDCLDEKQC KQCANKVLQH MKAVQADQER ERQRRLEVER EAEKKREAKQ RAKEAQEREL RKREKAEEKE RRRKEYDA |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores. |
| Protein Name | Leucine-Rich Repeat-Containing Protein 59Ribosome-Binding Protein P34P34 Cleaved Into - Leucine-Rich Repeat-Containing Protein 59 - N-Terminally Processed |
| Database Links | |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Ii Membrane ProteinEndoplasmic Reticulum MembraneNucleus EnvelopeLocalization In The Nuclear Envelope Depends Upon The Nuclear Import MachineryIncluding Kpnb1 |
| Alternative Protein Names | Leucine-Rich Repeat-Containing Protein 59 proteinRibosome-Binding Protein P34 proteinP34 Cleaved Into - Leucine-Rich Repeat-Containing Protein 59 - N-Terminally Processed proteinLRRC59 proteinPRO1855 protein |
Information sourced from Uniprot.org