Human LRRC25 protein (Recombinant) (C-His) (STJP013724)

Name: Human LRRC25 protein (Recombinant) (C-His) (STJP013724)
SKU: STJP013724-100
Price: 575.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP013724-100

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Short Description	Recombinant-Human LRRC25-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Function	Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting RIGI for autophagic degradation. Interacts specifically with ISG15-associated RIGI to promote interaction between RIGI and the autophagic cargo receptor p62/SQSTM1 to mediate RIGI degradation via selective autophagy. Also plays a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.
Protein Name	Leucine-Rich Repeat-Containing Protein 25 Monocyte And Plasmacytoid-Activated Protein
Database Links
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein Cytoplasm
Alternative Protein Names	Leucine-Rich Repeat-Containing Protein 25 protein Monocyte And Plasmacytoid-Activated Protein protein LRRC25 protein MAPA protein UNQ6169 protein PRO20174 protein

Information sourced from Uniprot.org