Human LMP2/PSMB9 protein (Recombinant) (His-Tag) (STJP017134)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human LMP2/PSMB9-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 50mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PSMB9 |
| Gene ID | 5698 |
| Uniprot ID | PSB9_HUMAN |
| Accession Number | NP_002791.1 |
| Immunogen | Human |
| Immunogen Region | 21-219aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity. |
| Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. |
| Protein Name | Proteasome Subunit Beta Type-9Low Molecular Mass Protein 2Macropain Chain 7Multicatalytic Endopeptidase Complex Chain 7Proteasome Chain 7Proteasome Subunit Beta-1iReally Interesting New Gene 12 Protein |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Proteasome Subunit Beta Type-9 proteinLow Molecular Mass Protein 2 proteinMacropain Chain 7 proteinMulticatalytic Endopeptidase Complex Chain 7 proteinProteasome Chain 7 proteinProteasome Subunit Beta-1i proteinReally Interesting New Gene 12 Protein proteinPSMB9 proteinLMP2 proteinPSMB6i proteinRING12 protein |
Information sourced from Uniprot.org