Biotinylated Human LILRB3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Human LILRB3/CD85a/ILT5 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001649)

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STJP001649
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Short Description :Recombinant-Human LILRB3/CD85a/ILT5-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Host:HEK293
Note:STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Biotin
Dilution Range:Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Formulation:Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Storage Instruction:The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin:Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol:LILRB3Uniprot ID=LIRB3_HUMAN"
Immunogen:DNA sequence encoding Human LILRB3/CD85a/ILT5 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Immunogen Region:Gly24-Glu443
Post Translational Modifications Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-595 and Tyr-625 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2.
Function May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3
Lir-3
Leukocyte Immunoglobulin-Like Receptor 3
Cd85 Antigen-Like Family Member A
Immunoglobulin-Like Transcript 5
Ilt-5
Monocyte Inhibitory Receptor Hl9
Cd Antigen Cd85a
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 protein
Lir-3 protein
Leukocyte Immunoglobulin-Like Receptor 3 protein
Cd85 Antigen-Like Family Member A protein
Immunoglobulin-Like Transcript 5 protein
Ilt-5 protein
Monocyte Inhibitory Receptor Hl9 protein
Cd Antigen Cd85a protein
LILRB3 protein
ILT5 protein
LIR3 protein

Information sourced from Uniprot.org

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