Human LILRB2 (Leukocyte immunoglobulin-like receptor subfamily B member 2) CLIA Kit for Quantitative Detection

Name: Human LILRB2 (Leukocyte immunoglobulin-like receptor subfamily B member 2) CLIA Kit for Quantitative Detection
SKU: STJC0000700
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

STJC0000700

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

General Information

Short Description	This human LILRB2 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes in serum, plasma and other biological fluids.
Applications	CLIA
Reactivity	Human
Sensitivity	18.75pg/mL
Detection Limit	31.25~2000pg/mL
Note	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Product Properties

Storage Instruction	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time	3.5h
Detection	Chemiluminescence

Target Information

Gene Symbol	LILRB2
Gene ID	10288
Uniprot ID	LIRB2_HUMAN
Specificity	This kit recognizes Human LILRB2 in samples. No significant cross-reactivity or interference between Human LILRB2 and analogues was observed.
Sample Type	Serum, plasma and other biological fluids

Additional Info

Tissue Specificity	Expressed in monocytes and at lower levels in myeloid and plasmacytoid dendritic cells. Expressed in tolerogenic IL10-producing dendritic cells. Expressed in myeloid-derived suppressor cells during pregnancy. Detected at low levels in natural killer (NK) cells. Expressed in B cells.
Post Translational Modifications	Phosphorylated on tyrosine residues. Dephosphorylated by PTPN6.
Function	Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Protein Name	Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 Lir-2 Leukocyte Immunoglobulin-Like Receptor 2 Cd85 Antigen-Like Family Member D Immunoglobulin-Like Transcript 4 Ilt-4 Monocyte/Macrophage Immunoglobulin-Like Receptor 10 Mir-10 Cd Antigen Cd85d
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative CLIA Names	Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 CLIA kit Lir-2 CLIA kit Leukocyte Immunoglobulin-Like Receptor 2 CLIA kit Cd85 Antigen-Like Family Member D CLIA kit Immunoglobulin-Like Transcript 4 CLIA kit Ilt-4 CLIA kit Monocyte/Macrophage Immunoglobulin-Like Receptor 10 CLIA kit Mir-10 CLIA kit Cd Antigen Cd85d CLIA kit LILRB2 CLIA kit ILT4 CLIA kit LIR2 CLIA kit MIR10 CLIA kit
Specificity	This kit recognizes Human LILRB2 in samples. No significant cross-reactivity or interference between Human LILRB2 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item	Specifications	Storage
Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Sample Type	Range (%)	Average Recovery (%)
Serum(n=8)	87-99	92
EDTA plasma(n=8)	101-117	108
Cell culture media(n=8)	91-106	97

	Intra-assay Precision	Intra-assay Precision	Intra-assay Precision	Inter-assay Precision	Inter-assay Precision	Inter-assay Precision
Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	93.76	263.95	925.19	87.48	257.17	1005.66
Standard deviation	7.70	19.56	102.88	8.91	26.31	115.35
CV (%)	8.21	7.41	11.12	10.19	10.23	11.47

Citations

View product citations for antibody STJC0000700 on CiteAb