Human LFA-3/CD58 protein (Recombinant) (C-hFc&His) (STJP001027)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human LFA-3/CD58 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Phe 29-Arg 215 ) of human CD58 (Accession #BC005930) fused with an Fc, 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human LFA-3/CD58-C-hFc&His protein was developed in hek293 cells using the region Phe 29-Arg 215. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | 1.Measured by its binding ability in a functional ELISA.Immobilized Human CD2 at 2 Mu g/mL (100 Mu L/well) can bind Human CD58 with a linear range of 1.22-34.4 ng/mL.|2.Measured by its binding ability in a functional ELISA. Immobilized CD58 (LFA-3) M |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CD58 |
| Gene ID | 965 |
| Uniprot ID | LFA3_HUMAN |
| Immunogen | Recombinant Human LFA-3/CD58 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Phe 29-Arg 215 ) of human CD58 (Accession #BC005930) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Region | Phe 29-Arg 215 |
| Immunogen Sequence | FSQQIYGVVYGNVTFHVPSN VPLKEVLWKKQKDKVAELEN SEFRAFSSFKNRVYLDTVSG SLTIYNLTSSDEDEYEMESP NITDTMKFFLYVLESLPSPT LTCALTNGSIEVQCMIPEYY NSHRGLIMYSWDCPMEQCKR NSTSIYFKMENDLPQKIQCT LSNPLFNTTSSIILTTCIPS SGHSRHR |
Additional Info
| Protein Name | Lymphocyte Function-Associated Antigen 3Ag3Surface Glycoprotein Lfa-3Cd Antigen Cd58 |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Lymphocyte Function-Associated Antigen 3 proteinAg3 proteinSurface Glycoprotein Lfa-3 proteinCd Antigen Cd58 proteinCD58 proteinLFA3 protein |
Information sourced from Uniprot.org