Human LETM1 protein (Recombinant) (N-His) (STJP007637)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LETM1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8Β°C for frequent use. Store at-20 to-80Β°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | LETM1 |
| Gene ID | 3954 |
| Uniprot ID | LETM1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu231-Thr426 |
Additional Info
| Function | Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Also functions as an electroneutral mitochondrial proton/potassium exchanger. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization. |
| Protein Name | Mitochondrial Proton/Calcium Exchanger ProteinElectroneutral Mitochondrial K(+/H(+ExchangerKheLeucine Zipper-Ef-Hand-Containing Transmembrane Protein 1 |
| Database Links | Reactome: R-HSA-8949215Reactome: R-HSA-9013408Reactome: R-HSA-9865881 |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Protein Names | Mitochondrial Proton/Calcium Exchanger Protein proteinElectroneutral Mitochondrial K(+/H(+Exchanger proteinKhe proteinLeucine Zipper-Ef-Hand-Containing Transmembrane Protein 1 proteinLETM1 protein |
Information sourced from Uniprot.org