Human LEFTY2 protein (Recombinant) (N-His) (STJP012960)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LEFTY2-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM His-HCl, 10% Trehalose, 4% Mannitol, 100mM NaCl, 0.1% Tween 80, pH 5.5. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | LEFTY2 |
| Gene ID | 7044 |
| Uniprot ID | LFTY2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Phe78-Pro366 |
Additional Info
| Post Translational Modifications | The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner. |
| Function | Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding. |
| Protein Name | Left-Right Determination Factor 2Endometrial Bleeding-Associated FactorLeft-Right Determination Factor AProtein Lefty-2Protein Lefty-ATransforming Growth Factor Beta-4Tgf-Beta-4 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-1181150Reactome: R-HSA-1433617 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Left-Right Determination Factor 2 proteinEndometrial Bleeding-Associated Factor proteinLeft-Right Determination Factor A proteinProtein Lefty-2 proteinProtein Lefty-A proteinTransforming Growth Factor Beta-4 proteinTgf-Beta-4 proteinLEFTY2 proteinEBAF proteinLEFTA proteinLEFTYA proteinTGFB4 proteinPSEC0024 protein |
Information sourced from Uniprot.org