Human LDB1 protein (Recombinant) (N-His) (STJP005644)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LDB1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | LDB1 |
| Gene ID | 8861 |
| Uniprot ID | LDB1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp112-Gln411 |
Additional Info
| Post Translational Modifications | Ubiquitinated by RLIM/RNF12, leading to its degradation by the proteasome. |
| Function | Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state. |
| Protein Name | Lim Domain-Binding Protein 1Ldb-1Carboxyl-Terminal Lim Domain-Binding Protein 2Clim-2Lim Domain-Binding Factor Clim2Hldb1Nuclear Lim Interactor |
| Database Links | Reactome: R-HSA-8939236Reactome: R-HSA-9010553Reactome: R-HSA-9733709Reactome: R-HSA-9752946 |
| Cellular Localisation | NucleusColocalizes With Slk At Leading Edges |
| Alternative Protein Names | Lim Domain-Binding Protein 1 proteinLdb-1 proteinCarboxyl-Terminal Lim Domain-Binding Protein 2 proteinClim-2 proteinLim Domain-Binding Factor Clim2 proteinHldb1 proteinNuclear Lim Interactor proteinLDB1 proteinCLIM2 protein |
Information sourced from Uniprot.org