Human LCP1 protein (Recombinant) (N-His) (STJP004083)

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STJP004083
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LCP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LCP1
Gene ID: 3936
Uniprot ID: PLSL_HUMAN
Immunogen Region: Ser5-Lys233
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin cytoskeleton and targeting to peripheral cell projections.
Function Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
Protein Name Plastin-2
L-Plastin
Lc64p
Lymphocyte Cytosolic Protein 1
Lcp-1
Database Links Reactome: R-HSA-8950505
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Cell Projection
Ruffle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Relocalizes To The Immunological Synapse Between Peripheral Blood T-Lymphocytes And Antibody-Presenting Cells In Response To Costimulation Through Tcr/Cd3 And Cd2 Or Cd28
Associated With The Actin Cytoskeleton At Membrane Ruffles
Relocalizes To Actin-Rich Cell Projections Upon Serine Phosphorylation
Alternative Protein Names Plastin-2 protein
L-Plastin protein
Lc64p protein
Lymphocyte Cytosolic Protein 1 protein
Lcp-1 protein
LCP1 protein
PLS2 protein

Information sourced from Uniprot.org

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