This LAMR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Applications
ELISA
Reactivity
Human
Sensitivity
29pg/mL
Detection Limit
78.1-5000pg/mL
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Storage Instruction
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
tissue homogenates, cell lysates or other biological fluids.
Additional Info
Tissue Specificity
Post Translational Modifications
Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association. Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
Function
Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. (Microbial infection) Acts as a receptor for the Adeno-associated viruses 2,3,8 and 9. (Microbial infection) Acts as a receptor for the Dengue virus. (Microbial infection) Acts as a receptor for the Sindbis virus. (Microbial infection) Acts as a receptor for the Venezuelan equine encephalitis virus. (Microbial infection) Acts as a receptor for the pathogenic prion protein. (Microbial infection) Acts as a receptor for bacteria.
Protein Name
Small Ribosomal Subunit Protein Us237 Kda Laminin Receptor Precursor37lrp37/67 Kda Laminin ReceptorLrp/Lr40s Ribosomal Protein Sa67 Kda Laminin Receptor67lrColon Carcinoma Laminin-Binding ProteinLaminin Receptor 1LamrLaminin-Binding Protein Precursor P40Lbp/P40Multidrug Resistance-Associated Protein Mgr1-AgNem/1chd4
Cell MembraneCytoplasmNucleus67lr Is Found At The Surface Of The Plasma MembraneWith Its C-Terminal Laminin-Binding Domain Accessible To Extracellular Ligands37lrp Is Found At The Cell SurfaceIn The Cytoplasm And In The NucleusColocalizes With Ppp1r16b In The Cell Membrane
Alternative ELISA Names
Small Ribosomal Subunit Protein Us2 ELISA kit37 Kda Laminin Receptor Precursor ELISA kit37lrp ELISA kit37/67 Kda Laminin Receptor ELISA kitLrp/Lr ELISA kit40s Ribosomal Protein Sa ELISA kit67 Kda Laminin Receptor ELISA kit67lr ELISA kitColon Carcinoma Laminin-Binding Protein ELISA kitLaminin Receptor 1 ELISA kitLamr ELISA kitLaminin-Binding Protein Precursor P40 ELISA kitLbp/P40 ELISA kitMultidrug Resistance-Associated Protein Mgr1-Ag ELISA kitNem/1chd4 ELISA kitRPSA ELISA kitLAMBR ELISA kitLAMR1 ELISA kit
