Human LAMC2 (Laminin Gamma 2) Sandwich ELISA Kit (STJE0010259)
SPECIFICATIONS
General Information
| Short Description | This LAMC2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.26ng/mL |
| Detection Limit | 0.781-50ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | LAMC2 |
| Gene ID | 3918 |
| Uniprot ID | LAMC2_HUMAN |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli. |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate (CS). CS attachment is on either Ser-803 or Ser-805. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. |
| Protein Name | Laminin Subunit Gamma-2Cell-Scattering Factor 140 Kda SubunitCsf 140 Kda SubunitEpiligrin Subunit GammaKalinin Subunit GammaKalinin/Nicein/Epiligrin 100 Kda SubunitLadsin 140 Kda SubunitLaminin B2t ChainLaminin-5 Subunit GammaLarge Adhesive Scatter Factor 140 Kda SubunitNicein Subunit Gamma |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-446107Reactome: R-HSA-8874081Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative ELISA Names | Laminin Subunit Gamma-2 ELISA kitCell-Scattering Factor 140 Kda Subunit ELISA kitCsf 140 Kda Subunit ELISA kitEpiligrin Subunit Gamma ELISA kitKalinin Subunit Gamma ELISA kitKalinin/Nicein/Epiligrin 100 Kda Subunit ELISA kitLadsin 140 Kda Subunit ELISA kitLaminin B2t Chain ELISA kitLaminin-5 Subunit Gamma ELISA kitLarge Adhesive Scatter Factor 140 Kda Subunit ELISA kitNicein Subunit Gamma ELISA kitLAMC2 ELISA kitLAMB2T ELISA kitLAMNB2 ELISA kit |
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Information sourced from Uniprot.org