Human LAMC2 (LAMC2) Antibody Pair (STJAP00889)
General Information
| Short Description | This LAMC2 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R05-1N-4/R08-7J-3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | LAMC2 |
| Gene ID | 3918 |
| Uniprot ID | LAMC2_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli. |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate (CS). CS attachment is on either Ser-803 or Ser-805. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. |
| Protein Name | Laminin Subunit Gamma-2Cell-Scattering Factor 140 Kda SubunitCsf 140 Kda SubunitEpiligrin Subunit GammaKalinin Subunit GammaKalinin/Nicein/Epiligrin 100 Kda SubunitLadsin 140 Kda SubunitLaminin B2t ChainLaminin-5 Subunit GammaLarge Adhesive Scatter Factor 140 Kda SubunitNicein Subunit Gamma |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-446107Reactome: R-HSA-8874081Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Pair Names | Laminin Subunit Gamma-2 antibody pairCell-Scattering Factor 140 Kda Subunit antibody pairCsf 140 Kda Subunit antibody pairEpiligrin Subunit Gamma antibody pairKalinin Subunit Gamma antibody pairKalinin/Nicein/Epiligrin 100 Kda Subunit antibody pairLadsin 140 Kda Subunit antibody pairLaminin B2t Chain antibody pairLaminin-5 Subunit Gamma antibody pairLarge Adhesive Scatter Factor 140 Kda Subunit antibody pairNicein Subunit Gamma antibody pairLAMC2 antibody pairLAMB2T antibody pairLAMNB2 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human LAMC2 (LAMC2) Antibody Pair (STJAP00889)
This antibody pair detects human LAMC2 (Laminin Subunit Gamma-2), corresponding to UniProt entry Q13753. Reactivity has been confirmed for human samples only.
Both the capture and detection antibodies are rabbit-derived monoclonal IgGs, with clone IDs R05-1N-4 and R08-7J-3 respectively. Both were raised against a recombinant protein immunogen and purified by affinity chromatography.
This antibody pair has been validated for use in ELISA. It is intended for sandwich ELISA development, though specific assay parameters such as working concentrations and detection range are to be determined by the end user.
Both antibodies are supplied unconjugated and are formulated in 0.01M PBS at pH 7.2. Researchers developing a sandwich ELISA will need to conjugate the detection antibody or use an appropriate secondary detection system.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquots should be kept at -20°C, and repeated freeze/thaw cycles should be avoided to maintain activity.
Concentration, sensitivity, and detection range data are not specified for this product. Working concentrations and assay sensitivity should be determined empirically by the end user during assay optimization.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.