Human LAMC2 (LAMC2) Antibody Pair (STJAP00889)
SPECIFICATIONS
ClonalityMonoclonal/Monoclonal
HostRabbit/Rabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein
General Information
| Short Description | This LAMC2 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R05-1N-4/R08-7J-3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | LAMC2 |
| Gene ID | 3918 |
| Uniprot ID | LAMC2_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | The large variant is expressed only in specific epithelial cells of embryonic and neonatal tissues. In 17-week old embryo the small variant is found in cerebral cortex, lung, and distal tubes of kidney, but not in epithelia except for distal tubuli. |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate (CS). CS attachment is on either Ser-803 or Ser-805. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. |
| Protein Name | Laminin Subunit Gamma-2Cell-Scattering Factor 140 Kda SubunitCsf 140 Kda SubunitEpiligrin Subunit GammaKalinin Subunit GammaKalinin/Nicein/Epiligrin 100 Kda SubunitLadsin 140 Kda SubunitLaminin B2t ChainLaminin-5 Subunit GammaLarge Adhesive Scatter Factor 140 Kda SubunitNicein Subunit Gamma |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-2022090Reactome: R-HSA-2214320Reactome: R-HSA-3000157Reactome: R-HSA-3000171Reactome: R-HSA-446107Reactome: R-HSA-8874081Reactome: R-HSA-9913351 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMajor Component |
| Alternative Antibody Pair Names | Laminin Subunit Gamma-2 antibody pairCell-Scattering Factor 140 Kda Subunit antibody pairCsf 140 Kda Subunit antibody pairEpiligrin Subunit Gamma antibody pairKalinin Subunit Gamma antibody pairKalinin/Nicein/Epiligrin 100 Kda Subunit antibody pairLadsin 140 Kda Subunit antibody pairLaminin B2t Chain antibody pairLaminin-5 Subunit Gamma antibody pairLarge Adhesive Scatter Factor 140 Kda Subunit antibody pairNicein Subunit Gamma antibody pairLAMC2 antibody pairLAMB2T antibody pairLAMNB2 antibody pair |
Information sourced from Uniprot.org