Human LAGE3 protein (Recombinant) (His-Tag) (STJP018150)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human LAGE3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% Glycerol, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LAGE3 |
| Gene ID | 8270 |
| Uniprot ID | LAGE3_HUMAN |
| Accession Number | NP_006005 |
| Immunogen | Human |
| Immunogen Region | 1-143aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMRDADAD AGGGADGGDG RGGHSCRGGV DTAAAPAGGA PPAHAPGPGR DAASAARGSR MRPHIFTLSV PFPTPLEAEI AHGSLAPDAE PHQRVVGKDL TVSGRILVVR WKAEDCRLLR ISVINFLDQL SLVVRTMQRF GPPVSR |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex. |
| Protein Name | Ekc/Keops Complex Subunit Lage3L Antigen Family Member 3Protein Eso-3Protein Itba2 |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Ekc/Keops Complex Subunit Lage3 proteinL Antigen Family Member 3 proteinProtein Eso-3 proteinProtein Itba2 proteinLAGE3 proteinDXS9879E proteinESO3 proteinITBA2 protein |
Information sourced from Uniprot.org