Human LACTb (Lactamase Beta) Sandwich ELISA Kit (STJE0010247)

SPECIFICATIONS
STJE0010247
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General Information

Short DescriptionThis LACTb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
ApplicationsELISA
ReactivityHuman
Sensitivity0.093ng/mL
Detection Limit0.312-20ng/mL
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Storage InstructionStore the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time4.5 hrs

Target Information

Gene SymbolLACTB
Gene ID114294
Uniprot IDLACTB_HUMAN
Sample Typetissue homogenates or other biological fluids.

Additional Info

Tissue Specificity Expressed predominantly in skeletal muscle.
Post Translational Modifications
Function Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism. Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism. It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein. Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism.
Protein Name Serine Beta-Lactamase-Like Protein Lactb - Mitochondrial
Database Links
Cellular Localisation Mitochondrion
Alternative ELISA Names Serine Beta-Lactamase-Like Protein Lactb - Mitochondrial ELISA kit
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output

Information sourced from Uniprot.org

Citations

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