Human Lactate Dehydrogenase A/LDHA protein (Recombinant) (His-Tag) (STJP016629)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Lactate Dehydrogenase A/LDHA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 300unit/mg, in which one unit will convert 1.0 umole of pyruvate to L-lactate and beta-NAD per minute at pH 7.5 at 37C. |
Target Information
| Gene Symbol | LDHA |
| Gene ID | 3939 |
| Uniprot ID | LDHA_HUMAN |
| Accession Number | NP_005557 |
| Immunogen | Human |
| Immunogen Region | 1-332aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Predominantly expressed in anaerobic tissues such as skeletal muscle and liver. |
| Post Translational Modifications | ISGylated. |
| Function | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). |
| Protein Name | L-Lactate Dehydrogenase A ChainLdh-ACell Proliferation-Inducing Gene 19 ProteinLdh Muscle SubunitLdh-MRenal Carcinoma Antigen Ny-Ren-59 |
| Database Links | Reactome: R-HSA-70268Reactome: R-HSA-9861718 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | L-Lactate Dehydrogenase A Chain proteinLdh-A proteinCell Proliferation-Inducing Gene 19 Protein proteinLdh Muscle Subunit proteinLdh-M proteinRenal Carcinoma Antigen Ny-Ren-59 proteinLDHA proteinPIG19 protein |
Information sourced from Uniprot.org