Human KRT2 protein (Recombinant) (N-His) (STJP004634)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KRT2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KRT2 |
| Gene ID | 3849 |
| Uniprot ID | K22E_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Cys7-Leu160 |
Additional Info
| Function | Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins. Plays a role in the establishment of the epidermal barrier on plantar skin. |
| Protein Name | Keratin - Type Ii Cytoskeletal 2 EpidermalCytokeratin-2eCk-2eEpithelial Keratin-2eKeratin-2 EpidermisKeratin-2eK2eType-Ii Keratin Kb2 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Keratin - Type Ii Cytoskeletal 2 Epidermal proteinCytokeratin-2e proteinCk-2e proteinEpithelial Keratin-2e proteinKeratin-2 Epidermis proteinKeratin-2e proteinK2e proteinType-Ii Keratin Kb2 proteinKRT2 proteinKRT2A proteinKRT2E protein |
Information sourced from Uniprot.org