Human KMT2D protein (Recombinant) (N-His) (STJP007830)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KMT2D-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KMT2D |
| Gene ID | 8085 |
| Uniprot ID | KMT2D_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Val5381-Met5536 |
Additional Info
| Function | Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription. |
| Protein Name | Histone-Lysine N-Methyltransferase 2dLysine N-Methyltransferase 2dAll1-Related ProteinMyeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 2 |
| Database Links | Reactome: R-HSA-201722Reactome: R-HSA-3214841Reactome: R-HSA-3769402Reactome: R-HSA-5617472Reactome: R-HSA-8936459Reactome: R-HSA-9772755Reactome: R-HSA-9818564Reactome: R-HSA-9841922 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Histone-Lysine N-Methyltransferase 2d proteinLysine N-Methyltransferase 2d proteinAll1-Related Protein proteinMyeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 2 proteinKMT2D proteinALR proteinMLL2 proteinMLL4 protein |
Information sourced from Uniprot.org