Human KLRG1/CLEC15A protein (Recombinant) (N-His) (STJP009547)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KLRG1/CLEC15A-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KLRG1 |
| Gene ID | 10219 |
| Uniprot ID | KLRG1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser74-Lys186 |
Additional Info
| Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. |
| Protein Name | Killer Cell Lectin-Like Receptor Subfamily G Member 1C-Type Lectin Domain Family 15 Member AItim-Containing Receptor Mafa-LMafa-Like ReceptorMast Cell Function-Associated Antigen |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Killer Cell Lectin-Like Receptor Subfamily G Member 1 proteinC-Type Lectin Domain Family 15 Member A proteinItim-Containing Receptor Mafa-L proteinMafa-Like Receptor proteinMast Cell Function-Associated Antigen proteinKLRG1 proteinCLEC15A proteinMAFA proteinMAFAL protein |
Information sourced from Uniprot.org