Human Klotho beta/KLB protein (Recombinant) (C-His) (STJP002079)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Klotho beta/KLB Protein is produced by mammalian expression system. The target protein is expressed with sequence (Met30-Thr983) of human Beta Klotho (Accession #) fused with a His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Klotho beta/KLB-C-His protein was developed in hek293 cells using the region Met30-Thr983. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Immobilized Human Klotho at 1 Mu g/mL (100 Mu L/Well).Dose response curve for Anti-Klotho Ab.1 with the EC50 of 0.4 Mu g/ml determined by ELISA.|Immobilized Human Klotho at 2 Mu g/ml (100 Mu L/Well).Dose response curve for Anti-Klotho Ab. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | KLB |
| Gene ID | 152831 |
| Uniprot ID | KLOTB_HUMAN |
| Immunogen | Recombinant Human Klotho beta/KLB Protein is produced by mammalian expression system. The target protein is expressed with sequence (Met30-Thr983) of human Beta Klotho (Accession #) fused with a His tag at the C-terminus. |
| Immunogen Region | Met30-Thr983 |
| Immunogen Sequence | MSNGGLQRSVILSALILLRA VTGFSGDGRAIWSKNPNFTP VNESQLFLYDTFPKNFFWGI GTGALQVEGSWKKDGKGPSI WDHFIHTHLKNVSSTNGSSD SYIFLEKDLSALDFIGVSFY QFSISWPRLFPDGIVTVANA KGLQYYSTLLDALVLRNIEP IVTLYHWDLPLALQEKYGGW KNDTIIDIFNDYATYCFQMF GDRVKYWITIHNPYLVAWHG YGTGMHAPGEKGNLAAVYT |
Additional Info
| Protein Name | Beta-KlothoBklBetaklothoKlotho Beta-Like Protein |
| Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1257604Reactome: R-HSA-1307965Reactome: R-HSA-2219530Reactome: R-HSA-5654228Reactome: R-HSA-5654712Reactome: R-HSA-5654719Reactome: R-HSA-5654720Reactome: R-HSA-5654733Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Protein Names | Beta-Klotho proteinBkl proteinBetaklotho proteinKlotho Beta-Like Protein proteinKLB protein |
Information sourced from Uniprot.org