Human KLK7 protein (Recombinant) (N-GST) (STJP004839)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human KLK7-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KLK7 |
| Gene ID | 5650 |
| Uniprot ID | KLK7_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu23-Arg253 |
Additional Info
| Function | May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. |
| Protein Name | Kallikrein-7Hk7Serine Protease 6Stratum Corneum Chymotryptic EnzymeHscce |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-9725554 |
| Cellular Localisation | SecretedIn Ovarian CarcinomaSecreted And Also Observed At The Apical Membrane And In Cytoplasm At The Invasive Front |
| Alternative Protein Names | Kallikrein-7 proteinHk7 proteinSerine Protease 6 proteinStratum Corneum Chymotryptic Enzyme proteinHscce proteinKLK7 proteinPRSS6 proteinSCCE protein |
Information sourced from Uniprot.org