Human KLK11 protein (Recombinant) (N-His) (STJP006141)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP006141
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General Information

Short DescriptionRecombinant-Human KLK11-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolKLK11
Gene ID11012
Uniprot IDKLK11_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionLeu38-Asn282

Additional Info

Post Translational Modifications About 40% of KLK11 is inactivated by internal cleavage after Arg-188. This proteolytic inactivation may be effected by plasminogen.
Function Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.
Protein Name Kallikrein-11
Hk11
Hippostasin
Serine Protease 20
Trypsin-Like Protease Cleaved Into - Kallikrein-11 Inactive Chain 1 - Kallikrein-11 Inactive Chain 2
Database Links
Cellular Localisation Isoform 1: Secreted
Isoform 2: Golgi Apparatus
Secreted
Alternative Protein Names Kallikrein-11 protein
Hk11 protein
Hippostasin protein
Serine Protease 20 protein
Trypsin-Like Protease Cleaved Into - Kallikrein-11 Inactive Chain 1 - Kallikrein-11 Inactive Chain 2 protein
KLK11 protein
PRSS20 protein
TLSP protein
UNQ649 protein
PRO1279 protein

Information sourced from Uniprot.org

Citations

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